Track 30: Coronavirus Pathogenesis

 What is Corona virus Pathogenesis?

Coronavirus pathogenesis refers to the biological processes and mechanisms through which coronaviruses, including SARS-CoV, MERS-CoV, and SARS-CoV-2 (COVID-19), cause disease in humans. It involves how the virus enters the body, replicates, triggers immune responses, and leads to clinical symptoms ranging from mild respiratory illness to severe acute respiratory distress.

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Deadline Alert!

Don’t miss the chance to be part of this landmark event. The conference will take place from September 02–04, 2025 at Novotel Al Barsha, Dubai, UAE. 20-08-2025 is the deadline for registrations, speaker submissions, and abstract entries.



Causes

The causes of coronavirus infections are linked to several factors:

  • Viral Transmission: Spread through respiratory droplets, aerosols, and contaminated surfaces.
  • Zoonotic Origin: Coronaviruses often originate in animals (bats, camels) and cross over to humans.
  • Host Susceptibility: Individuals with weakened immunity, chronic illnesses, or advanced age are more vulnerable.
  • Mutations: Genetic variations in the virus increase transmissibility and pathogenicity.

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Types of Coronavirus

Human coronaviruses are broadly classified into common cold-causing strains and severe pathogenic strains:

  • Mild Pathogenic Coronaviruses:
    • HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1 → cause mild upper respiratory tract infections.
  • Highly Pathogenic Coronaviruses:
    • SARS-CoV (2002) – Severe Acute Respiratory Syndrome.
    • MERS-CoV (2012) – Middle East Respiratory Syndrome.
    • SARS-CoV-2 (2019) – COVID-19 pandemic.

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Prohibition (Prevention & Control)

To prevent coronavirus infections and their complications, the following strategies are vital:

  • Vaccination – Immunization remains the most effective tool against SARS-CoV-2.
  • Hygiene Practices – Regular hand washing, sanitization, and use of masks in crowded areas.
  • Social & Public Health Measures – Isolation of infected individuals, ventilation of indoor spaces, and limiting mass gatherings during outbreaks.
  • Medical Preparedness – Early diagnosis, antiviral treatments, and strengthening healthcare infrastructure.

 

Conclusion

Coronavirus pathogenesis highlights the complex interaction between viral mechanisms and host immune response. While mild coronaviruses continue to circulate seasonally, highly pathogenic strains like SARS-CoV-2 have reshaped global health systems. Advances in virology, diagnostics, vaccines, and therapeutics are key to reducing mortality and improving resilience against future outbreaks.

The upcoming 15th Emirates Pathology, Digital Pathology & Cancer Conference (September 02–04, 2025 | Dubai, UAE) provides an essential platform to explore emerging insights into viral pathogenesis, diagnostics, and preventive strategies that can shape the future of global health.

 

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